| Publications in peer-reviewed journals | |
Loi P, Yuan Q, Torres D, Delbauve S, Laute MA, Lalmand MC, Pétein M, Goriely S, Goldman M, Flamand V. IRF3 deficiency leads to IL-17-mediated liver ischemia-reperfusion injury. Hepatology 2013; 57: 351-361.
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Aksoy E, Taboubi S, Torres D, Delbauve S, Hachani A, Whitehead MA, Pearce WP, Berenjeno-Martin I, Nock G, Filloux A, Beyaert R, Flamand V, Vanhaesebroeck B. The p110δ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock. Nat Immunol 2012; 13: 1045-1054.
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Antoine P, Olislagers V, Huygens A, Lecomte S, Liesnard C, Donner C, Marchant A. Functional exhaustion of CD4+ T lymphocytes during primary cytomegalovirus infection. J Immunol 2012; 189: 2665-2672.
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Charbonnier LM, Le Moine A. Rapamycin as immunosuppressant in murine transplantation model. Methods Mol Biol 2012; 821: 435-445.
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Charbonnier LM, Vokaer B, Lemaître PH, Field KA, Leo O, Le Moine A. CTLA4-Ig restores rejection of MHC class-II mismatched allografts by disabling IL-2-expanded regulatory T cells. Am J Transplant 2012; 12: 2313-2321.
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Dauby N, Goetghebuer T, Kollmann TR, Levy J, Marchant A. Uninfected but not unaffected: chronic maternal infections during pregnancy, fetal immunity, and susceptibility to postnatal infections. Lancet Infect Dis 2012; 12 : 330-340.
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Debock I, Delbauve S, Dubois A, Pétein M, Leo O, Goldman M, Flamand V. Th17 alloimmunity prevents neonatal establishment of lymphoid chimerism in IL-4-deprived mice. Am J Transplant 2012; 12: 81-89.
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Kollmann TR, Levy O, Montgomery RR, Goriely S. Innate immune function by Toll-like receptors: distinct responses in newborns and the elderly. Immunity 2012; 37: 771-783.
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Welsby I, Hutin D, Leo O. Complex roles of members of the ADP-ribosyl transferase super family in immune defences: Looking beyond PARP1. Biochem Pharmacol 2012; 84:11-20
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Wilmar A, Lonez C, Vermeersch M, Andrianne M, Pérez-Morga D, Ruysschaert JM, Vandenbranden M, Leo O, Temmerman S. The cationic lipid, diC14 amidine, extends the adjuvant properties of aluminum salts through a TLR-4- and caspase-1-independent mechanism. Vaccine 2012; 30: 414-424.
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Adams B, Dubois A, Delbauve S, Debock I, Lhommé F, Goldman M, Flamand V. Expansion of regulatory CD8(+) CD25 (+) T cells after neonatal alloimmunization. Clin Exp Immunol 2011; 163: 354-361.
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Debock I, Flamand V. Th2 alloimmunity counteracts Th17-type response in the neonatal establishment of lymphoid chimerism. Chimerism 2011; 2: 117-119.
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Johnson J, Molle C, Aksoy E, Goldman M, Goriely S, Willems F. A conventional protein kinase C inhibitor targeting IRF-3-dependent genese differentially regulates IL-12 family members. Mol Immunol 2011; 48: 1484-1493.
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Moens E, Brouwer M, Dimova T, Goldman M, Willems F, Vermijlen D. IL-23R and TCR signalling drives the generation of neonatal Vγ9Vδ T cells expressing high levels of cytotoxic mediators and producing IFN-γ and IL-17. J Leukoc Biol 2011, 89; 743-752.
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Van Rompaey N, Le Moine A. Myeloid derived suppressor cells (MDSC) : characterization and expansion in models of endotoxemia and transplantation. Methods Mol Biol 2011; 677: 169-180.
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Weatherly K, Braun MY. Organ transplantation. Modulation of T cell activation pathways initiated by cell surface receptors to suppress graft rejection. Methods Mol Biol 2011; 677: 419-430.
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De Wit D, Goldman M. Adjuvant activity on human cells in vitro. Methods Mol Biol 2010; 626 : 103-116.
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Dubois A, Deruytter N, Adams B, Kanda A, Delbauve S, Fleury S, Torres D, François A, Petein M, Goldman M, Dombrowicz D, Flamand V. Regulation of Th2 responses and allergic inflammation through bystander activation od CD8+ T lymphocytes in early life. J Immunol 2010; 185 : 884-891.
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Langlet C, Springael C, Johnson J, Thomas S, Flamand V, Leitges M, Goldman M, Aksoy E, Willems F. PKC-alpha controls MYD88-dependent TLR/IL-1R signaling and cytokine production in mouse and human dendritic cells. Eur J Immunol 2010 ; 40 : 505-515.
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Legat A, Thomas S, Hermand P, Van Mechelen M, Goldman M, De Wit D. CD14-independent responses induced by a synthetic lipid A mimetic. Eur J Immunol 2010; 40: 797-802.
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Molle C, Goldman M, Goriely S. Critical role of the IFN-stimulated gene factor 3 complex in TLR-mediated IL-27p28 gene expression revealing a two-step activation process. J Immunol 2010; 184 : 1784-1792.
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Moser M, Leo O. Key concepts in immunology. Vaccine 2010; 28 (S3) : C2-C13.
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Nguyen M, Leuridan E, Zhang T, De Wit D, Willems F, Van Damme P, Goldman M, Goriely S. Acquisition of adult-like TLR4 and TLR9 responses during the first year of life. PLoSONE 2010; 5 : e10407.
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Noval Rivas M, Hazzan M, Weatherly K, Gaudray F, Salmon I, Braun M. NK cells regulate graft-versus-host disease by limiting the antigen-driven expansion of CD4-positive T cells. J Immunol 2010; 184 : 6790-6798.
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Roufosse F, Weller P. Practical approach to the patient with marked hypereosinophilia. J Allergy Clin Immunol, 2010; 126 : 39-44.
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Roufosse F, de Lavareille A, Schandené L, Cogan E, Georgelas A, Wagner L, Xi L, Raffield M, Goldman M, Gleich GJ, Klion A. Mepolizumab as a corticosteroid-sparing agent in lymphocytic variant hypereosinophilic syndrome. J Allergy Clin Immunol 2010 ; 126 : 828-835.
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Vermijlen D, Brouwer M, Donner C, Liesnard C, Tackoen M, Van Rysselberge M, Twité N, Goldman M, Marchant A, Willems F. Human cytomegalovirus elicits fetal γδ T cell responses in utero. J Exp Med 2010; 207 : 807-821.
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Vokaer B, Van Rompaey N, Lemaître P, Lhommé F, Kubjak C, Benghiat FS, Iwakura Y, Petein M, Field KA, Goldman M, Le Moine A, Charbonnier LM. Critical role of regulatory T cells in Th17-mediated minor antigen-disparate rejection. J Immunol 2010 ; 185 : 3417-3425.
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Benghiat FS, Charbonnier LM, Vokaer B, De Wilde V, Le Moine A. Interleukin 17-producing T helper cells in alloimmunity. Transplant Rev, 2009; 23: 11-18
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De Wilde V, Van Rompaey N, Hill M, Lebrun J.F, Lemaître P, Lhommé F, Kubjak C, Vokaer B, Oldenhove G, Charbonnier L.M, Cuturi M.C, Goldman M, Le Moine A Endotoxin-induced myeloid-derived suppressor cell inhibits alloimmune responses via oxygenase-1. Am J Transplant 2009; 9 : 1-14.
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Donckier V, Craciun L, Lucidi V, Buggenhout A, Troisi R, Rogiers X, Boon N, Gustot T, Moreno C, Bourgeois N, Colle I, Van Vlierberghe H, Nagy N, Praet M, Dernies T, Amrani M, Stordeur P, de Hemptinne B, Goldman M. Acute liver transplant rejection upon immunosuppression withdrawal in a tolerance induction trial: potential role of IFNγ-secreting CD8+ T cells. Transplantation 2009; 87: S91-S95.
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Donckier V, Sanchez-Fueyo A, Craciun L, Lucidi V, Buggenhout A, Troisi R, Rogiers X, Bourgeois N, Boon N, Moreno C, Colle I, Van Vlierbergne H, de Hemptinne B, Goldman M. Induction of tolerance in solid organ transplantation: the rationale to develop clinical protocols in liver transplantation. Transpl Proc 2009; 41:603-188
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Garçon N, Goldman M. Boosting vaccine power. Sci Am 2009; 301:72-79.
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Goldman M, Wood K. Transplantation research: will we ever reach the Holy Grail ? Transplantation 2009; 87:S99-100.
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Goldman M, Wood K. Transplanting transplantation tolerance in the clinic: where are we, where do we go? Clin Exp Immunol 2009; 156:185-188
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Goriely S, Cavoy R, Goldman M. Interleukin-12 family members and type I interferons in Th17-mediated inflammatory disorders. Allergy 2009; 64:702-709
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Le Moine A, Vokaer B, Charbonnier LM. A brief focus on memory cells in transplantation. Transplant Proc 2009 ; 41 : 3361-3362.
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Noval Rivas M, Weatherly K, Hazzan M, Vokaer B, Dremier S, Gaudray F, Goldman M, Salmon I, Braun M. Reviving function in CD4+ T cells adapted to persistent systemic antigen. J Immunol 2009; 183:4284-4291.
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Ravoet M, Sibille C, Gu C, Libin M, Haibe Kains B, Sotiriou C, Goldman M, Roufosse F, Willard Gallo K. Molecular profiling of CD3-CD4+ tycells from patients with the lymphocytic variant of hypereosinophilic syndrome reveals targeting of growth control pathways. Blood 2009; 114:2969-2983.
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Renneson J, Dutta B, Goriely S, Danis B, Lecomte S, Laes J.F, Tabi Z, Goldman M, Marchant A. IL-12 and type I IFN response of neonatal myeloid DC to human CMV infection. Eur J Immunol 2009; 39:2789-2799.
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Roufosse F. Hypereosinophilic syndrome variants : diagnostic and therapeutic considerations. Haematologica 2009; 94:1188-1193.
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Willems F, Vollstedt S, Suter M. Phenotype and function of neonatal DC. Eur J Immunol 2009; 39 : 26-35.
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Alegre ML, Leemans J, Le Moine A, Florquin S, De Wilde V, Chong A, Goldman M The multiple facets of Toll-like receptors in transplantation biology Transplantation 2008 ; 86 : 1-9.
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Benghiat FS, Craciun L, De Wilde V, Dernies T, Kubjak C, Lhomme F, Goldman M, Le Moine A. IL-17 production elicited by allo-MHC class II recognition depends on CD25posCD4pos T cells. Transplantation 2008 ; 85 : 943-949.
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Buonocore S, Ouled Haddou N , Moore F, Florquin S, Paulart F, Heirman C, Thielemans K, Goldman M, Flamand V. Neutrophil-dependent tumor rejection and priming of tumoricidal CD8+ T cell response induced by dendritic cells overexpressing CD95L J Leuk Biol 2008;84: 713-20
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Danis B, George TC, Goriely S, Dutta B, Renneson J, Gatto L, Fitzgerald-Bocarsly P, Goldman M, Willems F, De Wit D. Interferon regulatory factor 7 dependent responses are deficient in cord blood plasmacytoid dendritic cells Eur J Immunol 2008 ; 37 : 507-517.
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De Wilde V, Benghiat FS, Noval Rivas M, Lebrun JF, Kubjak C, Oldenhove G, Petein M, Goldman M, Le Moine A. Endotoxin hyperresponsiveness upon CD4+ T cell reconstitution in lymphopenic mice : control by natural regulatory T cells. Eur J Immunol 2008 ; 38 : 48-53.
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Goldman M, Donckier V. Transplantation tolerance : European union meets the challenge Rev Med Brux 2008 ; 29 : 41-44.
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Goldman M. Sublingual immunotherapy : the quest for innovative adjuvants. Clin Exp Allergy 2008; 38:1705-1706
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Goriely S, Goldman M. Interleukin-12 family members and the balance between rejection and tolerance. Curr Opin Organ Transplant 2008 ; 13 : 4-9.
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Goriely S, Neurath M, Goldman M. How microorganisms tip the balance between interleukin-12 family members Nature Rev Immunol 2008 ; 82 : 86.
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Kapessidou P, Poulin L, Dumoutier L , Goldman M, Renauld JC, Braun MY The absence of interleukin-22 accelerates the rejection of full major histocompatibility complex-disparate heart allografts Transpl P 2008 ; 40 : 1593-1597.
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Kaye S, Miles D, Antoine P, Burny W, Ojuola B, Kaye P, Rowland-Jones S, Whittle H, van der Sande M, Marchant A. Virological and immunological correlates of mother to child transmission of cytomegalovirus in The Gambia. J Infect Dis 2008 ; 197 : 1307-1314.
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Li Z, Benghiat FS, Charbonnier LM, Kubjak C, Rivas MN, Cobbold SP, Waldmann H, De Wilde V, Petein M, Schuind F, Goldman M, Le Moine A. CD8+ T-Cell depletion and rapamycin synergize with combined coreceptor/stimulation blockade to induce robust limb allograft tolerance in mice. Am J Transplant 2008 ; 8 : 2527-2536.
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Miles D, van der Sande M, Jeffries D, Kaye S, Ojuola O, Sanneh M, Cox M, Palmero M, Touray E, Waight P, Rowland-Jones S, Whittle H, Marchant A. Maintenance of large subpopulations of differentiated CD8 T-cells two years after cytomegalovirus infection in Gambian infants. PLoS ONE 2008 : e2905.
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Miles D, van der Sande M, Kaye S, Crozier S, Ojuola O, Palmero M, Sanneh M, Touray E, Rowland-Jones S, Whittle H, Ota M, Marchant A. Effects of antenatal and postnatal environments on CD4 T cell responses to Mycobacterium bovis BCG in healthy infants in The Gambia. Clin Vaccine Immunol 2008 ; 15 : 995-1002.
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Stubbe M, Vanderheyde N, Pircher H, Goldman M, Marchant A. Characterization of a subset of antigen-specific human central memory CD4+ T lymphocytes producing effector cytokines. Eur J Immunol 2008 ; 38 : 273-282.
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Aksoy E, Albarani V, Nguyen M, Laes JF, Ruelle JL, De Wit D, Willems F, Goldman M, Goriely S. IRF3-dependent responses to LPS are selectively blunted in human cord blood. Blood 2007 ; 109 : 2887-2893.
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Alegre ML, Florquin S, and Goldman M. Cellular mechanisms underlying acute graft rejection: time for reassessment. Curr Opin Immunol 2007; 19: 563-568.
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Beuneu C, Vosters O, Pipeleers D, Pradier O, Goldman M, Verhasselt V. N-Acetylcysteine derivative inhibits procoagulant activity of human islet cells. Diabetologia 2007 ; 50 : 343-347.
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Craciun L, DiGiambattista M, Laub R, Goldman M, Dupont E. Apoptosis : a target for potentiation of UV-induced IL-1Ra synthesis by IVIg. Immunol Lett 2007 ; 110 : 36-41.
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Craciun L, Stordeur P, Troisi R, Le Moine A, Toungouz M, Colle I, Van Vlierberghe H, Loi P, Lucici V, Preat M, de Hemptinne B, Goldman M, Donckier V. A rapid test of alloreactivity based on interleukin-2 mRNA expression might identify liver transplant recipients with donor-specific hyporesponsiveness. Transplant P 2007 ; 39 : 2665-2667.
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Dremier S, Milenkovic M, Blancquaert S, Dumont JE, Døskeland SO, Maenhaut C, Roger PP. Cyclic adenosine 3',5'-monophosphate (cAMP)-dependent protein kinases, but not exchange proteins directly activated by cAMP (Epac), mediate thyrotropin/cAMP-dependent regulation of thyroid cells. Endocrinology 2007 ; 148 : 4612-4622.
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Feunou P, Vanwetswinkel S, Gaudray F, Goldman M, Matthys P, Braun MY. Foxp3+ CD25+ T regulatory cells stimulate IFN-γ-independent CD152-mediated activation of tryptophan catabolism that provides dendritic cells with immune regulatory activity in mice unresponsive to SEB1. J Immunol 2007 ; 179 : 910-917.
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Goldman M, Wood K. European Research on cell and organ transplantation: towards novel opportunities ? Transplant Int 2007; 20 : 1016-1019.
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Goldman M. Translational mini-review series on Toll-like receptors : Toll-like receptor ligands as novel pharmaceuticals for allergic disorders. Clin Exp Immunol 2007 ; 147 : 208-216.
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Goriely S, Goldman M. The interleukin-12 family : new players in transplantation immunity ? Am J Transplant 2007 ; 7 : 278-284.
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Goriely S, Goldman M. From tolerance to autoimmunity: is there a risk in early life vaccination? J Comp Pathol 2007 ; S57-S61.
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Johnson J, Albarani V, Goldman M, Willems F, Aksoy E. Protein kinase C alpha is involved in Toll-like receptor 3-mediated IRF-3 activation and type I IFN-b synthesis. J Biol Chem 2007 ; 282 : 15022-15032.
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Laporte M, Trakatelli M, Vereecken P, Blocklet D, Lespagnard M, Petein M, Goldman M, Velu T, Heenen M. Skin biopsies in DC vaccines for stage III-IV melanoma patients : role of neutrophils. Arch Dermatol Res 2007 ; 299 : 483-486.
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Li Z, Benghiat FS, Kubkak C, Schuind F, Goldman M, Le Moine A. Donor T cell development in host thymus after heterotopic limb transplantation in mice. Transplantation 2007 ; 83 : 815-818.
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Molle C, Nguyen M, Flamand V, Trottein F, De Wit D, Willems F, Goldman M, Goriely S. IL-27 synthesis induced by TLR ligation critically depends on IFN regulatory factor 3. J Immunol 2007 ; 178 : 7607-7615.
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Moore F, Buonocore S, Aksoy E, Ouled-Haddou, N, Goriely S, Lazarova E, Paulart F, Heiman C, Vaeremans E, Thielemans K, Goldman M, Flamand V. An alternative pathway of NF-κB activation results in maturation and T cell priming activity of dendritic cells overexpressing a mutated IκB. J Immunol 2007 ; 178 : 1301-1311
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Roufosse F, Cogan E, Goldman M. Lymphocytic variant hypereosinophilic syndromes. Immunol Allergy Clin North Am 2007 ; 27 : 389-413.
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Roufosse F, Goldman M, Cogan E. Hypereosinophilic syndromes. Orphanet J Rare Dis 2007 ; 2 : 37.
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Sadis C, Teske G, Stokman G, Kubjak C, Claessen N, Moore F, Loi P, Diallo B, Barvais L, Goldman M, Florquin S, Le Moine A. Nicotine protects kidney from renal ischemia/reperfusion injury through the cholinergic anti-inflammatory pathway. PLoS ONE 2007 ; 2 : e469. doi : 10. 371/journal.pone.0000469.
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Springael C, Thomas S, Rahmouni S, Vandamme A, Goldman M, Willems F, Vosters O. Rottlerin inhibits human T cell responses. Mol Pharmacol 2007 ; 73 : 515-525.
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Stordeur P. Assays for alloreactive responses by PCR. Methods Mol Biol 2007; 407 : 209-224.
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Donckier V, Troisi R, Le Moine A, Ricciardi S, Colle I, Van Vlierberghe H, Toungouz M, Craciun L, Libin M, Praet M, Noens L, Stordeur P, Andrien M, Lambermont M, Gelin M, Bourgeois N, Adler M, De Hemptinne B, Goldman M.-1528. Early immunosuppression withdrawal after living donor liver transplantation using post-transplant high dose anti-thymocyte globulin and donor hematopoietic stem cell infusion. Liver Transpl 2006 ; 12 : 1523-1528.
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Galle C, Schandené L, Dereume JP, Goldman M, Duftner C, Dejaco C, Schirmer M. CD8+ T-cell subpopulations in human abdominal aortic aneurysm lesion. Arterioscl Thromb Vasc Biol 2006 ; 26 : 19-20.
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Goriely S, Molle C, Nguyen M, Albarani V, Ouled Haddou N, Lin R, De Wit D, Flamand V, Willems F, Goldman M. Interferon regulatory factor 3 is involved in Toll like receptor (TLR)4- and TLR3-induced IL-12p35 gene activation. Blood 2006 ; 107 : 1078-1084.
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Kapessidou P, Habran C, Buonocore S, Flamand V, Barvais L, Goldman M, Braun MY. The replacement of graft endothelium by recipient-type cells conditions allograft rejection mediated by indirect pathway CD4+T cells. Transplantation 2006 ; 81 : 726-735.
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Roufosse F, Goldman M, Cogan E. Hypereosinophilic syndrome : lymphoproliferative and myeloproliferative variants. Semin Respir Crit Care Med 2006; 27 : 158-170.
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Stubbe M, Vanderheyde N, Goldman M, Marchant A. Antigen-specific central memory CD4+ T lymphocytes produce multiple cytokines and proliferate in vivo in humans. J Immunol 2006 ; 177 : 8185-8190.
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Tonon S , Badran B, Benghiat FS, Goriely S, Flamand V, Willard-Gallo K, Willems F, Goldman M, De Wit D. Pertussis toxin activates adult and neonatal naive human CD4+ T lymphocytes. Eur J Immunol 2006 ; 36 : 1794-1804.
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Vanden Eijnden S, Goriely S, De Wit D, Goldman M, Willems F. Preferential production of the IL-12(p40)/IL-23(p19) heterodimer by dendritic cells from human newborns. Eur J Immunol 2006 ; 36 : 21-26.
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Aksoy E, Vanden Berghe W, Detienne S, Amraoui Z, Fitzgerald KA, Haegeman G, Goldman M, Willems F. Inhibition of phosphoinositide 3-kinase enhances TRIF-dependent NF-kB activation and IFN-β synthesis downstream of Toll-like receptor 3 and 4. Eur J Immunol 2005 ; 35 : 2200-2209.
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Andreae J, Galle C, Magdorf K, Staab D, Meyer L, Goldman M, Querfeld U. Severe atherosclerosis of the aorta and development of peripheral T-cell lymphoma in an adolescent with angiolymphoid hyperplasia with eosinophilia. Br J Dermatol 2005 ; 152 : 1033-1038.
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Benghiat S, Graca L, Braun M, Detienne S, Moore F, Buonocore S, Flamand V, Waldmann H, Goldman M, Le Moine A. Critical influence of natural regulatory CD25+ T cells on the fate of allografts in the absence of immunosuppression. Transplantation 2005 ; 79 : 648-654.
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Benghiat S, Graca L, Braun MY, Detienne S, Moore F, Buonocore S, Waldmann H, Goldman M, Le Moine A. Critical influence of natural regulatory CD25+ T cells on the fate of allografts in absence of immunosuppression. Transplantation 2005 ; 79 : 648-654.
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Galle C, Schandené L, Stordeur P, Peignois Y, Ferreira J, Wautrecht JC, Dereume JP, Goldman M. Predominance of type 1 CD4+ T cells in human abdominal aortic aneurysm. Clin Exp Immunol 2005 ; 142 : 519-527.
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Marchant A, Goldman M. T cell-mediated immune responses in human newborns : ready to learn? Clin Exp Immunol 2005; 141 : 10-18.
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Ocmant A, Michils A, Schandené L, Peignois Y, Goldman M, Stordeur P. IL-4 and IL-13 mRNA real-time PCR quantification on whole blood to assess allergic response. Cytokine 2005 ; 31 : 375-381.
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Poulin L, Habran C, Stordeur P, Goldman M, McKenzie A, Van Snick J, Renauld JC, Braun MY. IL-9 stimulates the production of IL-5 in CD4+ T cells. Eur Cytokine Netw 2005 ; 16 : 1-7.
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Ravoet M, Sibille C, Roufosse F, Duvillier H, Sotiriou C, Schandené L, Martiat P, Goldman M, Willard-Gallo KE. 6q- is an early and persistent chromosomal aberration in the CD3-CD4+ T cell clones associated with the lymphocytic variant of hypereosinophilic syndrome. Haematologica 2005 ; 90 : 753-765.
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Renneson J, Salio M, Mazouz N, Goldman M, Marchant A, Cerundolo V. Mature dendritic cells differentiated in the presence of IFN-b and IL-3 prime functional antigen-specific CD8+ T cells. Clin Exp Immunol 2005 ; 139 : 468-475.
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Surquin M, Buonocore S, Le Moine A, Flamand V, Goldman M, Abramowicz D. The role of neutrophils during allograft rejection. Nephrol Ther 2005; 3 : 161-166.
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Surquin M, Le Moine A, Flamand V, Rombaut K, Demoor F, Salmon I, Goldman M, Abramowicz D. IL-4 deficiency prevents eosinophilic rejection and uncovers a role for neutrophils in the rejection of MHC class II disparate skin grafts. Transplantation 2005 ; 80 : 1485-1492.
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Vanden Eijnden S, Goriely S, De Wit D, Willems F, Goldman M. IL-23 upregulates IL-10 and induces IL-17 synthesis by polyclonally activated naive T cells in human. Eur J Immunol 2005 ; 35 : 469-475.
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Willard-Gallo KE, Badran BM, Ravoet M, Zerghe A, Burny A, Martiat P, Goldman M, Roufosse F, Sibille C. Defective CD3g gene transcription is associated with NFATc2 overexpression in the lymphocytic variant of hypereosinophilic syndrome. Exp Hematol 2005 ; 33 : 1147-1159.
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Ysebrant de Lendonck L, Ocmant A, Roufosse F, Cogan E. Predictive markers for development of severe organ involvement in patients with systemic sclerosis. Ann N Y Acad Sci 2005 ; 1051 : 455-464.
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Zhou L, Toungouz M, Donckier V, Andrien M, Troisi R, de Hemptinne B, Le Moine A, Dupont E, Goldman M, Stordeur P. A rapid test to monitor alloreactive responses in whole blood using real-time PCR. Transplantation 2005 ; 80 : 410-413.
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de Lavareille A, Prigogine C, Paulart F, Nagy N, Habran C, Oualed Haddou N, Le Moine A, Salmon I, Goldman M, Flamand V. Regulatory role of host CD8+ T lymphocytes in experimental graft-versus-host disease across a single MHC class II incompatibility. Transplantation 2005 ; 80 : 1293-1299.
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Aksoy E, Goldman M, Willems F. Protein Kinase C Epsilon : a new target to control inflammation and immune-mediated disorders. Int J Biochem Cell Biol 2004; 36 : 183-188.
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Beuneu C, Vosters O, Movahedi B, Remmelink M, Salmon I, Pipeleers D, Pradier O, Goldman M, Verhasselt V. Human pancreatic duct cells exert tissue factor-dependent procoagulant activity : relevance to islet transplantation. Diabetes 2004 ; 53 : 1407-1411.
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Buonocore S, Flamand V, Claessen N, Heeringa P, Goldman M, Florquin S. Dendritic cells overexpressing Fas-ligand induce pulmonary vasculitis in mice. Clin Exp Immunol 2004 ; 137 : 74-80.
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Buonocore S, Surquin M, Le Moine A, Abramowicz D, Flamand V, Godman M, Amplification of T cell responses by neutrophils: relevance to allograft immunity. Immunol Lett 2004; 94 : 163-166.
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Burny W, Liesnard C, Donner C, Marchant A. Epidemiology, pathogenesis and prevention of congenital cytomegalovirus infection. Expert Rev Anti-Infective Ther 2004; 2 : 881-894.
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Danis B, Goriely S, Dubois P, Fowler SW, Flamand V, Warnau M. Contrasting effects of coplanar versus non-coplanar PCB congeners on immunomodulation and CYP1A levels (determined using an adapted ELISA method) in the common sea star Asterias rubens L. Aquat Toxicol 2004 ; 69 : 371-383.
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De Wit D, Olislagers V, Goriely S, Vermeulen F, Wagner H, Goldman M, Willems F. Blood plasmacytoid dendritic cell responses to CpG oligodeoxynucleotides are impaired in human newborns. Blood 2004 ; 103 : 1030-1032.
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Donckier V, Troisi R, Toungouz M, Colle I, Van Vlierberghe H, Jacquy C, Martiat P, Stordeur P, Zhou L, Boon N, Lambermont M, Schandené L, Van Laethem J-L, Noens L, Gelin M, de Hemptinne B, Goldman M. Donor stem cells infusion after non myeloablative conditionning for tolerance induction to HLA mismatched adult living-donor liver graft. Transplant Immunol 2004 ; 13 : 139-146.
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Goldman M, Donckier V, Toungouz M. Hematopoietic stem cells as inducers of tolerance to solid organ transplants. Curr Opin Organ Transplant 2004; 9: 279-283.
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Goriely S, Van Lint C, Dadkhah R, Libin M, De Wit D, Demonté D, Willems F, Goldman M. A defect in nucleosome remodeling prevents IL-12 (p35) gene transcription in neonatal dendritic cells. J Exp Med 2004 ; 199 : 1011-1016.
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Loi P, Paulart F, Pajak B, Nagy N, Salmon I, Moser M, Goldman M, Flamand V. The fate of dendritic cells in a mouse model of liver ischemia / reperfusion injury. Transplant Proc 2004 ; 36 : 1275-1279.
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Moore F, Buonocore S, Paulart F, Thielemans K, Goldman M, Flamand V. Unexpected effects of viral inteleukin-10-secreting dendritic cells in vivo : preferential inhibition of Th2 responses. Transplant Proc 2004 ; 36 : 3260-3266.
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Roufosse F, Cogan E, Goldman M. Recent advances in pathogenesis and management of hypereosinophilic syndromes. Allergy 2004; 59 : 673-689.
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Vanderheyde N, Vandenabeele P, Goldman M, Willems F. Distinct mechanisms are involved in tumoristatic and tumoricidal activities of monocyte-derived dendritic cells. Immunol Lett 2004 ; 91 : 99-101.
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Verhasselt V, Vosters O, Beuneu C, Nicaise C, Stordeur P, Goldman M. Induction of FoxP3-expressing regulatory CD4+ T cells by human mature autologous dendritic cells. Eur J Immunol 2004 ; 34 : 762-772.
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Vosters O, Beuneu C, Nagy N, Movahedi B, Aksoy E, Salmon I, Pipeleers D, Goldman M, Verhasselt V. CD40 expression on human pancreatic duct cells: role in Nuclear Factor-kappa B activation and production of proinflammatory cytokines. Diabetologia 2004 ; 47 : 660-668.
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Zhou L, Schandené L, Mordvinov V, Chatelain P, Pradier O, Goldman M, Stordeur P. Trapidil inhibits monocyte CD40 expression by preventing IFN-gamma induced STAT-1 S727 phosphorylation. Int Immunopharmacol 2004 ; 4 : 863-871.
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Contributions to Original Studies
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Braconnier P, Del Marmol V, Broeders N, Kianda M, Massart A, Lemy A, Ghisdal L, Le Moine A, Madhoun P, Racapé J, Abramowicz D, Wissing KM. Combined introduction of anti-IL2 receptor antibodies, mycophenolic acid and tacrolimus: effect on malignancies after renal transplantation in a single-centre retrospective cohort study. Nephrol Dial Transplant 2012; 27: 2547-2553.
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Scheper W, van Dorp S, Kersting S, Pietersma F, Lindemans C, Hol S, Heijhuurs S, Sebestyen Z, Gründer C, Marcu-Malina V, Marchant A, Donner C, Plachter B, Vermijlen D, van Baarle D, Kuball J. γδT-cells elicited by CMV-reactivation after allo-SCT cross-recognize CMV and leukemia. Leukemia 2012, in press.
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Levy O, Goriely S, Kollmann TR. Immune response to vaccine adjuvants during the first year of life. Vaccine 2012, in press.
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Christensen JE, Fenger C, Issazadeh-Navikas S, Krug A, Liljestrøm P, Goriely S, Paludan SR, Finsen B, Christensen JP, Thomsen AR. Differential impact of interferon regulatory factor 7 in initiation of the type I interferon response in the lymphocytic choriomeningitis virus-infected central nervous system versus the periphery. J Virol 2012; 86: 7384-7392.
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Schillewaert S, Wacheul L, Lhomme F, Lafontaine D. The evolutionarily conserved protein Las1 is required for pre-rRNA processing at both ends of ITS2. Mol Cell Biol 2012; 32: 430-444.
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Vitry MA, De Trez C, Goriely S, Dumoutier L, Akira S, Ryffel B, Carlier Y, Letesson JJ, Muraille E. Crucial role of gamma interferon-producing CD4+ Th1 cells but dispensable function of CD8+ T cell, B cell, Th2, and Th17 responses in the control of Brucella melitensis infection in mice. Infect Immun 2012; 80: 4271-4280.
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Weiss G, Maaetoft-Udsen K, Stifter SA, Hertzog P, Goriely S, Thomsen AR, Paludan SR, Frøkiær H. MyD88 drives the IFN-β response to Lactobacillus acidophilus in dendritic cells through a mechanism involving IRF1, IRF3, and IRF7. J Immunol 2012; 189: 2860-2868.
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Hougardy JM, Broeders N, Kianda M, Massart A, Madhoun P, Le Moine A, Hoang AD, Mikhalski D, Wissing KM, Abramowicz D. Conversion from Prograf to Advagraf among kidney transplant recipients results in sustained decrease in tacrolimus exposure. Transplantation 2011; 91; 566-569.
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Blimkie D, Fortuno ES, Yan H, Cho P, Ho K, Turvey SE, Marchant A, Goriely S, Kollman TR. Variables to be controlled in the assesment of blood innate immune responses to Toll-like receptor stimulation. J Immunol Methods 2011; 366; 89-99.
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Flanagan KL, Klein SL, Skakkebaek NE, Marriott I, Marchant A, Selin L, Fish EN, Prentice AM, Whittle H, Benn CS, Aaby P. Sex differences in the vaccine-specific and non-targeted effects of vaccines. Vaccine 2011; 29: 2349-2354.
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Morampudi V, Braun MY, D'Souza S. Modulation of early β-defensin-2 production as a mechanism developed by type I Toxoplasma gondii to evade human intestinal immunity. Infect Immun 2011; 79 :2043-2050.
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Morampudi V, De Craeye S, Le Moine A, Detienne S, Braun MY, D'Souza S. Partial depletion of CD4(+)CD25(+)Foxp3(+) T regulatory cells significantly increases morbidity during acute phase Toxoplasma gondii infection in resistant BALB/c mice. Microbes Infect 2011; 13; 394-404.
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Uyttenhove C, Marillier RG, Tacchini-Cottier F, Charmoy M, Caspi RR, Damsker JM, Goriely S, Su D, Van Damme J, Struyf S, Opdenakker G, Van Snick J Technical advance: amine-reactive OVA multimers for auto-vaccination against cytokines and other mediators: perspectives illustrated for GCP-2 in L. major infection. J Leukoc Biol 2011; 89: 1001-1007.
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Burl S, Adetifa UJ, Cox M, Touray E, Ota MO, Marchant A, Whittle H, McShane H, Rowland-Jones S, Flanagan KL. Delaying bacillus Calmette-Guérin vaccination from birth to 4/12 months of age reduces postvaccination Th1 and IL-17 responses but leads to comparable mycobacterial responses at 9 months of age. J Immunol 2010; 185: 2620-2628.
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Dilek N, Van Rompaey N, Le Moine A, Vanhove B. Myeloid-derived suppressor cells in transplantation. Curr Opin Organ Transplant 2010 ; 15 : 765-768.
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Epalza C, Goetghebuer T, Hainaut M, Prayez F, Barlow P, Dediste A, Marchant A, Levy J. High incidence of invasive group B streptococcal infections in HIV-exposed uninfected infants. Paediatrics 2010; 126: e631-e638.
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Kahn JE, Grandpeix-Guyodo C, Marroun I, Catherinot E, Mellot F, Roufosse F, Blétry O. Sustained response to mepolizumab in refractory Churg-Strauss syndrome. J Allergy Clin Immunol 2010; 125: 267-270.
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Méric de Bellefon L, Heiman P, Kanaan SB, Azzouz DF, Rak JM, Martin M, Roudier J, Roufosse F, Lambert NC. Cells from a vanished twin as a source of microchimerism 40 years later. Chimerism 2010; 1: 56-60.
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Marichal T, Bedoret D, Mesnil C, Pichavant M, Goriely S, Trottein F, Cataldo D, Goldman M, Lekeux P, Bureau F, Desmet CJ. J Allergy Clin Immunol 2010; 126: 836-844.
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Meraviglia S, Eberl M, Vermijlen D, Todaro M, Buccheri S, Cicero G, La Mendola C, Guggino G, D'Asaro M, Orlando V, Scarpa F, Roberts A, Caccamo N, Stassi G, Dieli F, Hayday AC. In vivo manipulation of Vγ9Vδ2 T cells with zoledronate and low-dose interleukin-2 for immunotherapy of advanced breast cancer patients. Clin Exp Immunol 2010; doi:10.1111/j.1365-2249.2010.04167.x.
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Miqueu P, Degauque N, Guillet M, Giral M, Ruiz C, Pallier A, Braudeau C, Roussey-Kesler G, Ashton-Chess J, Doré JC, Thervet E, Legendre C, Hernandez-Fuentes MP, Warrens AN, Goldman M, Volk HD, Janssen U, Wood KJ, Lechler RI, Bertrand D, Sébille V, Soulillou JP, Brouard S. Analysis of the peripheral T-cell repertoire in kidney transplant patients. Eur J Immunol 2010 ; 40: 3280-3290.
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Poulin LF, Salio M, Griessinger E, Anjos-Afonso F, Craciun L, Chen JL, Keller AM, Joffre O, Zelenay S, Nye E, Le Moine A, Faure F, Donckier V, Sancho D, Cerundolo V, Bonnet D, Reis e Sousa C. Characterization of human DNGR-1+BDCA3+ leukocytes as putative equivalents of mouse CD8α+ dendritic cells. J Exp Med 2010; 6: 1261-1271.
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Raicevic G, Rouas R, Najar M, Stordeur P, Boufker H, Bron D, Martiat P, Goldman M, Toungouz Nevessignsky M, Lagneaux L. Inflammation modifies the pattern and the function of Toll-like receptors expressed by human mesenchymal stromal cells. Hum Immunol 2010; 71: 235-244.
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Sagoo P, Perucha E, Sawitzki B, Tomiuk S, Stephens D, Miqueu P, Chapman S, Craciun L, Sergeant R, Brouard S, Rovis F, Jimenez E, Ballow A, Giral M, Rebollo-Mesa I, Le Moine A, Braudeau C, Hilton R, Gerstmayer B, Bourcier K, Sharif A, Krajewska M, Lord G, Roberts I, Goldman M, Wood K, Newell K, Seyfert-Margolis V, Warrens A, Janssen U, Volk HD, Soulillou JP, Hernandez-Fuentes M, Lechler R. Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans. J Clin Invest 2010; doi:10.1172/JCI39922.
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Simon HU, Rothenberg ME, Bochner BS, Weller PF, Wardlaw AJ, Wechsler ME, Rosenwasser LJ, Roufosse F, Gleich GJ, Klion AD. Refining the definition of hypereosinophilic syndrome. J Allergy Clin Immunol 2010; 126: 45-49.
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Torres D, Dieudonné A, Ryffel B, Vilain E, Si-Tahar M, Pichavant M, Lassalle P, Trottein F, Gosset P. Double-stranded RNA exacerbates pulmonary allergic reaction through TLR3: implication of airway epithelium and dendritic cells. J Immunol 2010; doi:10.4049/jimmunol.0902833.
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White M, Lawless MW, O'Dwyer MJ, Grealy R, Connell BO, Stordeur P, Kelleher D, McManus R, Ryan T. Transforming growth factor b-1 and interleukin-17 gene transcription in peripheral blood mononuclear cells and the human response to infection. Cytokine 2010; 50: 322-327.
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Anckaert E, Adriaenssens T, Romero S, Dremier S, Smitz J. Unaltered imprinting establishment of key imprinted genes in mouse oocytes after in vitro follicle culture under variable follicle-stimulating hormone exposure. Int J Dev Biol 2009 ; 53 : 541-548.
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Bedoret D, Wallemacq H, Marichal T, Desmet C, Quesada Calvo F, Henry E, Closset R, Dewals B, Thielen C, Gustin P, de Leval L, Van Rooijen N, Le Moine A, Vanderplasschen A, Cataldo D, Drion PV, Moser M, Lekeux P, Bureau F. Lung interstitial macrophages alter dendritic cell functions to prevent airway allergy in mice. J Clin Invest 2009 ; 119 : 3723-3738.
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Ogbogu PU, Bochner BS, Butterfield JH, Gleich GJ, Huss-Marp J, Kahn JE, Leiferman JM, Nutman TB, Pfab F, Ring J, Rothenberg ME, Roufosse F, Sajous MH, Sheikh J, Simon D, Simon HU, SteinML, Wardlaw A, Weller PF, Klion AD. Hypereosinophilic syndromes: a multicenter, retrospective analysis of clinical characteristics and response to therapy. J Allergy Clin Immunol, 2009; 124: 1319-1325.
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Ravoet M, Sibille C, Gu C, Libin M, Haibe-Kains B, Sotiriou C, Goldman M, Roufosse F, Willard-Gallo K. Molecular profiling of CD3negCD4 T cells from patients with the lymphocytic variant of hypereosinophilic syndrome reveals targeting of growth control pathways Blood 2009 ; 114 : 2969-2983.
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Taccone FS, Stordeur P, De Backer D, Creteur J, Vincent JL. Gamma-globulin levels in patients with community aquired septic shock. Shock 2009; 32: 379-385.
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Van Coppernolle S, Verstichel G, Timmermans F, Velghe I, Vermijlen D, De Smedt M, Leclercq G, Plum J, Taghon T, Vandekerckhove B, Kerre T. Functionally mature CD4 and CD8 TCRalphabeta cells are generated in OP9-DL1 cultures from human CD34+ hematopoietic cells. J Immunol 2009; 183: 4859-4870.
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Driessens G, Gordower L, Nuttin L, Stordeur P, Blocklet D, Egrise D, Velu T, Bruyns C. Therapeutic efficacy of antitumor dendritic cell vaccinations correlates with persistent Th1 responses, high intratumor CD8+ T cell recruitment and low relative regulatory T cell infiltration. Cancer Immunol Immunother 2008; 57:1745-1756.
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Finan C, Ota M, Marchant A, Newport MJ. Natural variation in immune responses to neonatal Mycobacterium bovis Bacillus Calmette-Guerin (BCG) vaccination in a cohort of Gambian infants. PLoS ONE 2008; 3: e3485.
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Giebelen I, Le Moine A, van den Pangaart P, Sadis C, Goldman M, Florquin S, van der Poll T. Deficiency of α7 cholinergic receptors facilitates bacterial clearance in Escherichia coli peritonitis J Infect Dis 2008 ; 198 : 750-757.
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Guilliams M, Bosschaerts T, Hérin M, Hünig T, Loi P, Flamand V, De Baetselier P, Beschin A. Experimental expansion of the regulatory T cell population increases resistance to African trypanosomiasis. J Infect Dis 2008 ; 198 : 781-791.
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Miles D, van der Sande M, Kaye S, Crozier S, Ojuola O, Palmero M, Sanneh M, Touray E, Waight P, Rowland-Jones S, Wihittle H, Marchant A. CD4 T-cell responses to CMV mature slowly following infection in infancy : a prospective birth cohort study. J Infect Dis 2008 ; 197 : 658-662.ss.
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O'Dwyer MJ, Mankan AK, Ryan AW, Lawless MW, Stordeur P, Kellher D, McManus R, Ryan T. Characterization of tumor necrosis factor-alpha genetic variants and mRNA expression in patients with severe sepsis. Int J Immunogenet 2008; 35: 279-285.
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Rothenberg ME, Klion AD, Roufosse F, Kahn JE, Weller PF, Simon HU, Schwartz LB, Rosenwasser LJ, Ring J, Griffin EF, Haig AE, Frewer PI, Parkin JM, Gleich GJ. Mepolizumab HES Study Group. Treatment of patients with the hypereosinophilic syndrome with mepolizumab. N Engl J Med 2008; 358: 1215-1228.
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Schneeberger S, Gorantla V, van Riet R, Lanzetta M, Vereecken P, van HolderC, Rorive S, Remmelink M, Le Moine A, Abramowicz D, Zelger B, Kaufman C, Breidenbach W, Margreiter R, Schuind F. Atypical acute rejection after hand transplantation. Am J Transplant 2008 ; 8 : 688-696.
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Tanaka T, Legat A, Adam A, Steuve J, Gatot JS, Vandenbranden M, Ulianov L, Lonez C, Ruysschaert JM, Muraille E, Tuynder M, Goldman M, Jacquet A. DiC14-amidine cationic liposomes stimulate myeloid dendritic cells through Toll-like receptor 4. Eur J Immunol 2008 ; 38 : 1351-1357.
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Thielen C, Radermacher V, Trimeche M, Roufosse F, Goldman M, Boniver J, de Leval L. TARC and IL-5 expression correlates with tissue eosinophilia in peripheral T-cell lymphomas Leuk Res 2008 ; 32 : 1431-8.
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Vanhoutte F, Paget C, Breuilh L, Fontaine J, Vendeville C, Goriely S, Ryffel B, Faveeuw C, Trottein F. Toll-like receptor (TLR)2 and TLR3 synergy and cross-inhibition in murine myeloid dendritic cells. Immunol Lett 2008 ; 116 : 86-94.
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Brulet JM, Maudoux F, Thomas S, Thielemans K, Burny A, Leo O, Bex F, Hallez S. DNA vaccine encoding endosome-targeted human papillomavirus type 16 E7 protein generates CD4+ T cell-dependent protection. Eur J Immunol 2007 ; 37 : 376-384.
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Dijsselbloem N, Goriely S, Albarani V, Gerlo S, Francoz S, Marine JC, Goldman M, Haegeman G, Vanden Berghe W. A critical role for p53 in the control of NF-kappaB-dependent gene expression in TLR4-stimulated dendritic cells exposed to genistein. J Immunol 2007 ; 178 : 5048-5057.
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Guilliams M, Oldenhove G, Noel W, Herin M, Brys L, Loi P, Flamand V, Moser M, De Baetselier P, Beschin A. African trypanosomias : naturally occurring regulatory T cells favour trypanotolerance by limiting pathology associated with sustained type 1 inflammation. J Immunol 2007 ; 179 : 2748-2757.
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Habib M, Noval Rivas M, Chamekh M, Wieckowski S, Sun W, Bianco A, Trouche N, Chaloin O, Dumortier H, Goldman M, Guichard G, Fournel S, Vray B. Cutting edge : Small molecule CD40L mimetics promote control of parasitemia and enhance T cells producing interferon-g during experimental Trypanosoma cruzi infection. J Immunol 2007 ; 178 : 6700-6704.
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Huez S, Roufosse F, Vachiery JL, Pavelescu A; Derumeaux G, Wautrecht JC, Cogan E, Naeije R. Isolated right ventricular dysfunction in systemic sclerosis : latent pulmonary hypertension ? Eur Respir J 2007 ; 30 : 928-936.
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Miles DJ, van der Sande M, Jeffries D, Kaye S, Ismaili J, Ojuola O, Sanneh M, Touray ES, Waight P, Rowland-Jones S, Whittle H, Marchant A. Cytomegalovirus infection in Gambian infants leads to profound CD8 T cell differentiation. J Virol 2007 ; 81 : 5766-5776.
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Stephenne X, Vosters O, Najimi M, Beuneu C, Ngoc DK, Wijns W, Goldman M, Sokal E. Tissue factor-dependent procoagulant activity of isolated human hepatocytes : relevance to liver cell transplantation. Liver Transplant 2007 ; 13 : 599-606.
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Vanhoutte F, Breuilh L, Fontaine J, Mallevaey T, Vendeville C , Vasseur V, Capron M, Faveeuw C, Goriely S, Ryffel B, Trottein F. Toll-like receptor (TLR)2 and TLR3 sensing is required for dendritic cell activation, but dispensable to control Schistosoma mansoni infection and pathology. Microbes Infect 2007; 9 : 1606-1613.
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Vermijlen D, Ellis P, Langford C, Klein A, Engel R, Willimann K, Jomaa H, Hayday A, Ebert M. Distinct cytokine-driven responses of activated blood gd T cells : insights into unconventional T cell pleiotropy. J Immunol 2007 ; 178 : 4304-4314.
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Vosters O, Beuneu C, Goldman M, Verhasselt V. N-acetylcysteine derivative inhibits CD40-dependent proinflammatory properties of human pancreatic duct cells. Pancreas 2007 ; 36 : 363-368.
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van der Sande M, Kaye S, Miles D, Waight P, Jeffries D, Ojuola O, Palmero M, Pinder M, Ismaili J, Flanagan K, Aveika A, Zaman A, Rowland-Jones S, McConkey SJ, Whittle HC, Marchant A. Risk factors for and clinical outcome of congenital cytomegalovirus infection in a peri-urban West-African birth cohort. PLoS ONE 2007 ; 2 : e492, dooi:10.1371: journal.pone. 0000492.
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Clutterbuck EA, Salt P, Oh S, Marchant A, Beverley P, Pollard AJ. The kinetics and phenotype of the human B cell response following immunization with a heptavalent pneumococcal-CRM197 conjugate vaccine. Immunology 2006 ; 119 : 328-337.
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Lee YC, Newport MJ, Goetghebuer T, Siegrist CA, Weiss HA, Pollard AJ, Marchant A, the MRC Twin Study Group. Influence of genetic and environmental factors on the immunogenicity of HIV vaccine in Gambian twins. Vaccine 2006 ; 24 : 5335-5340.
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Marchant A, Pihlgren M, Goetghebuer T, Weiss HA, Ota MOC, Schlegel-Hauter SE, Whittle H, Lambert PH, Newport MJ, Siegrist CA, the MRC Gambia Twin Study Group. Predominant influence of environmental determinants on the persistence and avidity maturation of antibody responses to vaccines in infants. J Infect Dis 2006 ; 193 : 1598-1605.
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O'Dwyer MJ, Mankan AK, Stordeur P, O'Connell B, Duggan E, White M, Kelleher DP, McManus R, Ryan T. The occurrence of severe sepsis and septic shock are related to distinct patterns of cytokine gene expression. Shock 2006 ; 26 : 544-550.
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Ota M, Goetghebuer T, Vekemans J, Okoko BJ, Newport MJ, McAdam, KP, Marchant A. Dissociation between tuberculin skin test and in vitro IFN-g responses following neonatal BCG vaccination. J Trop Pediatrics 2006 ; 52 : 136-140.
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Aksoy E, Zouain C, Vanhoutte F, Fontaine J, Pavelka N, Thieblemont N, Willems F, Ricciardi-Castagnoli P, Goldman M, Capron M, Ryffel B, Trottein F. Double-stranded RNAs from the helminth parasite Schistosoma activate TLR3 in dendritic cells. J Biol Chem 2005 ; 280 : 277-283.
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Awomoyi A, Charurat N, Marchant A, Miller E, Blackwell JM, McAdam K, Newport MJ. Association of the interleukin-1b-511polymorphism with tuberculosis in a Gambian population sample. J Endotoxin Res 2005 ; 11 : 281-286
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Chamekh M, Vercruysse V, Habib M, Lorent M, Goldman M, Allaoui A, Vray B. Transfection of Trypanosoma cruzi with host CD40L results in improved control of parasite infection. Infect Immun 2005 ; 73 : 6552-6561.
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Duhant X, Suarez Gonzales N, Schandené L, Goldman M, Communi D, Boeynaems JM. Molecular mechanisms of extracellular adenine nucleotides-mediated inhibition of human CD4+ T lymphocyte activation. Purinergic Signalling 2005 ; 1 : 377-381.
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Graca L, Chen TC, Le Moine A, Cobbold S, Howie D, Waldmann H. Dominant tolerance : activation thresholds for peripheral generation of regulatory T cells. Trends Immunol 2005 ; 26 : 130-135.
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Keymeulen B, Vandemeulebroucke E, Ziegler A, Mathieu C, Kaufman L, Hale G, Gorus F, Goldman M, Walter M, Candon S, Schandené L, Crenier L, De Block C, Seigneurin JM, De Pauw P, Pierard D, Weets I, Rebello P, Bird P, Berrie E, Frewin M, Waldmann H, Ba Insulin needs following CD3 antibody therapy in new-onset type 1 diabetes. N Engl J Med 2005 ; 352 : 2598-2608.
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Marteau F, Suarez Gonzalez N, Communi D, Goldman M, Boeynaems JM, Communi D. Thrombospondin-1 and indoleamine 2,3-dioxygenase are major targets of extracellular ATP in human dendritic cells. Blood 2005 ; 106 : 3860-3866.
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Newport MJ, Goetghebuer T, Marchant A. Hunting for immune response regulatory genes : vaccination studies in infant twins. Expert Rev Vaccines 2005 ; 4 : 739-746.
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Stensballe LG, Nante E, Jensen IP, Kofoed P-E, Poulsen A, Jensen H, Newport M, Marchant A, Aaby P. Acute lower respiratory tract infections and respiratory syncytial virus in infants in Guinea-Bissau : a beneficial effect of BCG vaccination for girls. Community-based case-control study. Vaccine 2005 ; 23 : 1251-1257.
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Tassignon J, Burny W, Dahmani S, Zhou L, Stordeur P, Byl B, De Groote D. Monitoring of cellular responses after vaccination against Tetanus Toxoid : comparison of the measurement of IFN-g production by ELISA, ELISPOT, flow cytometry and real-time PCR. J Immunol Methods 2005 ; 276 : 69-77.
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Graca L, Le Moine A, Lin CY, Fairchild P, Cobbold D, Waldmann H Donor-specific transplantation tolerance: the paradoxical behavior of CD4+CD25+ T cells. Proc Natl Acad Sci USA 2004 ; 101 : 10122-10126.
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Newport MJ, Allen A, Awomoyi AA, Dunstan S, Marchant A, Sirugo G. The toll-like receptor 4 Asp299Gly variant : no influence on LPS responsiveness or susceptibility to pulmonary tuberculosis in The Gambia. Tuberculosis 2004 ; 84 : 347-352.
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Newport MJ, Goetghebuer T, Weiss HA, Whittle H, Siegrist CA, Marchant A T The MRC Gambian Twin Study Group. Genetic regulation of immune responses to vaccines in early life. Genes Immun 2004 ; 5 : 122-129.
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Ota M, Vekemans J, Schlegel-Haueter SE, Fielding K,Whittle H, Lambert PH, McAdam K, Siegrist CA, Marchant A. Hepatitis B immunization induces higher antibody and memory Th2 responses in new-borns than in adults. Vaccine 2004 ; 22 : 511-519.
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Papagno L, Spina CS, Marchant A, Salio M, Little S, Dong T, Waters A, Easterbrook P, Dunbar R, Shepherd D, Cerundolo V, Emery V, Griffiths P, Colon C, McMichael AJ, Richman DD, Rowland-Jones SL, Appay V. Activation and differentiation of CD8+ T-cells towards senescence in HIV-1 infection. Plos Biol 2004 ; 2 : 173-185.
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Van Der Sluijs KF, Van Elden LJ, Nijhuis M, Schuurman R, Pater JM, Florquin S, Goldman M, Jansen HM, Lutter R, Van Der Poll T. IL-10 is an important mediator of the enhanced susceptibility to pneumococcal pneumonia after influenza infection. J Immunol 2004 ; 172 : 7603-7609.
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Vandenberghe P, Wlodarska I, Michaux L, Zachée P, Boogaerts M, Vanstraelen D, Herregods MC, Van Hoof A, Selleslag D, Roufosse F, Maerevoet M, Verhoef G, De Wolf-Peeters C, Cools J, Gilliland G, Hagemeijer A, Marynen P. Clinical and molecular features of FIP1L1-PDGFRA positive hypereosinophilias. Leukemia 2004 ; 18 : 734-742.
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Vekemans J, Ota M, Sillah J, Fielding K, Alderson MR, Skeiky Y, Dalemans W, McAdam K, Lienhardt C, Marchant A. Immune responses to Mycobacterial antigens in the Gambian Population : implications for vaccines and immuno-diagnostic tests design. Infect Immun 2004 ; 72 : 381-388.
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Vandergheynst F, Ocmant A, Sordet C, Humbel RL, Goetz J, Roufosse F, Cogan E, Sibilia J. Anti-pm/scl antibodies in connective tissue disease : clinical and biological assessment of 14 patients. Clin Exp Rheumatol 2006 ; 24 : 129-133.
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Aksoy E, Taboubi S, Torres D, Delbauve S, Hachani A, Whitehead MA, Pearce WP, Berenjeno-Martin I, Nock G, Filloux A, Beyaert R, Flamand V, Vanhaesebroeck B. The p110δ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock. Nat Immunol 2012;13 :1045-1054.
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